CPD – Webinar: The Science of Cognition: Assessing Brain Health Through Organic Acid Metabolomics, Dr Christina Obrien. Notes: Organic acid metabolomics is a subfield of metabolomics that focuses on the analysis of organic acids, which are small molecule metabolites. These metabolites are indicators of biochemical activities within the body, particularly in the brain where they impact neurotransmitter synthesis and degradation. Analysing metabolomics offers a dynamic snapshot of the metabolic state through the fluctuations in metabolite levels. Studying these small molecules, provides insights into the systemic response to biological stress, disease states, and drug efficacy, making it an essential tool in biomedical research and precision medicine.This approach allows for a deeper understanding of the biochemical responses of the body to various physiological and pathological conditions, aiding in early disease detection, monitoring of disease progression, and personalised treatment strategies. The Organic Acid Test (part of the DUTCH Test, measures the levels of organic compounds in urine that are produced in the body as a part of many vital biochemical pathways. A defect in a particular pathway can result in either accumulation or lowered levels of its byproducts. Thus, measuring the levels of these markers can help to identify which metabolic process is blocked or compromised.
29/09/2025 | Comments Off on CPD – Webinar: The Science of Cognition: Assessing Brain Health Through Organic Acid Metabolomics, Dr Christina Obrien. Notes: Organic acid metabolomics is a subfield of metabolomics that focuses on the analysis of organic acids, which are small molecule metabolites. These metabolites are indicators of biochemical activities within the body, particularly in the brain where they impact neurotransmitter synthesis and degradation. Analysing metabolomics offers a dynamic snapshot of the metabolic state through the fluctuations in metabolite levels. Studying these small molecules, provides insights into the systemic response to biological stress, disease states, and drug efficacy, making it an essential tool in biomedical research and precision medicine.This approach allows for a deeper understanding of the biochemical responses of the body to various physiological and pathological conditions, aiding in early disease detection, monitoring of disease progression, and personalised treatment strategies. The Organic Acid Test (part of the DUTCH Test, measures the levels of organic compounds in urine that are produced in the body as a part of many vital biochemical pathways. A defect in a particular pathway can result in either accumulation or lowered levels of its byproducts. Thus, measuring the levels of these markers can help to identify which metabolic process is blocked or compromised.
