CPD – Webinar: Clinical Concepts: Is Histamine Intolerance Causing your Patients Gut Symptoms? Learn the Clues to Unexplained Functional Gut Presentations. Notes: Elizma Lambert discussed the difference between istamine Intolerance (HIT) and Mast Cell Activation Syndrome (MCAS), the role of histamine and histamine receptors in the gut and why it matters which cells release histamine. Factors involved in MCAS and HIT food, gut microbime, genes and enzymes and why some people develop sensitivities and other tolerance. She also discussed tools for practitioners to use to beter understand client’s needs and improve their outcomes with MCAS and HIT.